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Top 10 Clinical Decision Support Tools for 2025

Published June 18, 2025• Updated June 18, 2025• Last refreshed June 18, 2025

Top 10 Clinical Decision Support Tools for 2025

As the healthcare industry continues to evolve at a rapid pace, the use of artificial intelligence (AI) in Clinical Decision Support (CDS) systems is becoming increasingly crucial. These cutting-edge tools are transforming the way clinicians diagnose and treat patients, enabling greater precision, efficiency, and patient safety. AI in CDS has the potential to not only automate routine tasks but also to analyze large volumes of data and extract insightful patterns that can significantly improve patient outcomes.

Despite the promising potential, the adoption of AI in CDS is not without its hurdles. The healthcare sector faces various challenges, including data privacy concerns, the need for substantial investment in technology and training, and the lack of universally accepted standards for AI applications. Yet, the industry continues to push boundaries, seeking innovative solutions that can overcome these obstacles and deliver exceptional patient care. In this blog post, we will delve into the top 10 AI tools in the Clinical Decision Support category, their unique features, and how they are revolutionizing healthcare. We will also shed light on the current trends shaping this space and the hurdles that lie ahead. This post will serve as a valuable resource for healthcare professionals, decision-makers, and technology enthusiasts alike, offering deep insights into the exciting realm of AI in CDS.

1. RapidAI

Company: iSchemaView, Inc

Pricing: unclear

Target Customer: Enterprise

Summary: RapidAI offers a comprehensive suite of AI-powered clinical decision support tools designed to enhance stroke, trauma, aneurysm care, and more. Utilizing advanced algorithms, RapidAI provides real-time insights for faster, more confident decision-making across various healthcare settings. The platform aims to improve patient outcomes, drive operational efficiency, and strengthen financial viability through its clinically backed decision support.

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2. Navina

Company: Navina Technologies

Pricing: unclear

Target Customer: Clinic/Enterprise

Summary: Navina uses advanced AI to streamline the review of patient records, risk adjustment, quality management, and analytics for clinicians and care teams. By turning fragmented data from multiple sources into a coherent, single source of truth at the point of care, Navina enhances clinical decision-making, reduces administrative burden, and improves the efficiency and effectiveness of value-based care.

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3. Glass Health AI Clinical Decision Support

Company: Glass Health

Pricing: freemium

Target Customer: Clinician

Summary: Glass Health AI Clinical Decision Support platform aims to support clinicians by generating drafts of differential diagnoses, assessments & plans, and answers to clinical reference questions. It leverages AI to streamline the decision-making process, although it explicitly states its limitations in not being used for medical imaging, signals from in vitro diagnostic devices, or signal acquisition systems.

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4. InsightRX

Company: InsightRX, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: InsightRX offers a comprehensive platform that empowers healthcare organizations to individualize treatment at the point of care and during clinical development. By leveraging model-informed precision dosing, clinical decision support, and real-time clinical analytics, InsightRX aims to improve patient outcomes, reduce adverse drug events, and drive clinical innovation. The platform impacts over 1.2 million patients with more than 8.5 million doses personalized, trusted by 875 hospitals.

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5. Posos

Company: Posos SAS

Pricing: unclear

Target Customer: Clinician

Summary: Posos leverages AI to instantly dictate and refine prescriptions, understanding patient history to reduce risks and enhance care. It integrates seamlessly into EHR systems, offering a next-generation medical decision-support solution that empowers clinicians to prescribe with confidence and precision.

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6. Regard

Company: Regard

Pricing: unclear

Target Customer: Clinic/Enterprise

Summary: Regard is a cutting-edge platform that leverages the power of EHR data to provide actionable insights for healthcare providers. By analyzing all available patient data, it suggests diagnoses and generates care plans, effectively bridging the Clinical Insights Gap. This enables clinicians to uncover hidden insights in a patient's medical history, ensuring no vital context, undiagnosed conditions, or medications are missed, thereby improving quality, safety, and revenue through better care.

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7. VisualDx

Company: VisualDx

Pricing: subscription

Target Customer: Clinician

Summary: VisualDx is a comprehensive clinical decision support system that enhances diagnostic accuracy, aids therapeutic decisions, and improves patient safety by incorporating a vast medical image library. It supports clinicians across various specialties by providing tools for visual diagnosis, dermatology expertise, and integration with EHR systems, thereby addressing healthcare challenges such as dermatological care inefficiencies and health inequities.

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8. AwareCDI

Company: Iodine Software

Pricing: unclear

Target Customer: Enterprise

Summary: AwareCDI by Iodine Software leverages the power of CognitiveML™, a sophisticated AI engine, to identify and correct documentation gaps in clinical records. This solution is designed to prevent denials and ensure accurate, reliable reimbursement, thereby improving financial outcomes for healthcare organizations.

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9. AWARE Sepsis DART™

Company: Ambient Clinical Analytics

Pricing: unclear

Target Customer: Clinic

Summary: AWARE Sepsis DART™ is an innovative real-time communication platform that integrates into EHR workflows to monitor the sepsis treatment bundle. It uses smart notifications to reduce alert fatigue among clinicians and ensures timely communication of necessary actions to improve patient outcomes. The platform tracks patient information across care locations and staff shifts, minimizing errors and omissions in sepsis treatment.

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10. SaVia

Company: SaViaHealth

Pricing: unclear

Target Customer: Enterprise

Summary: SaVia offers a dynamic and personalized approach to sepsis care, providing real-time guidance and critical alerts to clinicians within their existing workflow. It aims to improve sepsis outcomes through targeted alerts, fast and easy pathway changes, and accelerated antibiotic delivery, ultimately increasing pathway adherence and reducing hospital stay lengths.

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In conclusion, these top 10 AI tools in the Clinical Decision Support category are revolutionizing healthcare by empowering clinicians with data-driven insights, enhancing patient outcomes, reducing costs, and streamlining operations. They are paving the way for a future where healthcare is smarter, safer, and more personalized. As AI continues to evolve, we can anticipate more sophisticated tools that will further transform the way we diagnose, treat, and manage diseases. It's an exciting time to be in the healthcare field, and we encourage each of you to explore these tools, understanding how they can enhance your practice or organization. Let's embrace the AI revolution, leveraging these powerful tools to redefine healthcare delivery and create a healthier world.

Featured Tools Quick Reference

Glass Health AI Clinical Decision Support logo

Glass Health AI Clinical Decision Support

Glass Health

AI-powered platform designed to enhance clinical decision-making for clinicians.

Target Customer: Clinician

VisualDx logo

VisualDx

VisualDx

A clinical decision support system specializing in dermatology and visual diagnosis.

Target Customer: Clinician

subscriptionVisit Website →
Regard logo

Regard

Regard

Transforms EHR data into actionable insights by analyzing patient data, suggesting diagnoses, and generating care plans.

Target Customer: Clinic/Enterprise

AWARE Sepsis DART™ logo

AWARE Sepsis DART™

Ambient Clinical Analytics

Real-time communication platform for sepsis treatment bundle monitoring and smart notifications.

Target Customer: Clinic

Posos logo

Posos

Posos SAS

AI-powered platform for enhancing medical prescription accuracy and efficiency.

Target Customer: Clinician

AwareCDI logo

AwareCDI

Iodine Software

AI-powered solution for Clinical Documentation Integrity.

Target Customer: Enterprise

SaVia logo

SaVia

SaViaHealth

Clinician-led, dynamic solution for overcoming the challenges of sepsis treatment by guiding clinicians at the point of care.

Target Customer: Enterprise

Navina logo

Navina

Navina Technologies

AI-powered platform that transforms complex, fragmented patient data into actionable insights for clinicians.

Target Customer: Clinic/Enterprise

InsightRX logo

InsightRX

InsightRX, Inc.

End-to-end solution for precision dosing intelligence to maximize therapeutic success.

Target Customer: Enterprise

RapidAI logo

RapidAI

iSchemaView, Inc

AI-driven clinical decision support tools for neurovascular, cardiac, vascular, and radiology care.

Target Customer: Enterprise

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